Structure of PDB 4e5x Chain D Binding Site BS01

Receptor Information
>4e5x Chain D (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>4e5x Chain F (length=9) Species: 39015 (Human T-cell lymphotropic virus type 1 (african isolate)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LLFGYPVYV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4e5x Crystal structure of adenovirus E3-19K bound to HLA-A2 reveals mechanism for immunomodulation.
Resolution1.95 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 V67 Q72 T73 V76 D77 Y84 Y99 Y116 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 V67 Q72 T73 V76 D77 Y84 Y99 Y116 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4e5x, PDBe:4e5x, PDBj:4e5x
PDBsum4e5x
PubMed23042604
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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