Structure of PDB 4chv Chain D Binding Site BS01

Receptor Information
>4chv Chain D (length=343) Species: 381 (Mesorhizobium loti) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LRIYAPLNAVLAAPGLLAVAALTIPDMSGRSRLALAALLAVIWGAYLLQL
AATLLKRRAGVVRDRTPKIAIDVLAVLVPLAAFLLDGSPDWSLYCAVWLL
KPLRDSTFFPVLGRVLANEARNLIGVTTLFGVVLFAVALAAYVIERDIQP
EKFGSIPQAMWWAVVTLSTTGYGDTIPQSFAGRVLAGAVMMSGIGIFGLW
AGILATGFYQEVRRGDFVRNWQLVAAVPLFQKLGPAVLVEIVRALRARTV
PAGAVICRIGEPGDRMFFVVEGSVSVATPNPVELGPGAFFGEMALISGEP
RSATVSAATTVSLLSLHSADFQMLCSSSPEIAEIFRKTALERR
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain4chv Chain A Residue 1350 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4chv Ligand-Induced Structural Changes in the Cyclic Nucleotide-Modulated Potassium Channel Mlok1
Resolution7.0 Å
Binding residue
(original residue number in PDB)		T175 T176 G177 T284 R348 R349
Binding residue
(residue number reindexed from 1)		T169 T170 G171 T278 R342 R343
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity
GO:0005267 potassium channel activity
GO:0030552 cAMP binding
GO:0042802 identical protein binding
GO:0044877 protein-containing complex binding
Biological Process
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4chv, PDBe:4chv, PDBj:4chv
PDBsum4chv
PubMed24469021
UniProtQ98GN8|CNGK1_RHILO Cyclic nucleotide-gated potassium channel mll3241 (Gene Name=mll3241)

[Back to BioLiP]