Structure of PDB 4ce4 Chain D Binding Site BS01

Receptor Information
>4ce4 Chain D (length=200) Species: 9825 (Sus scrofa domesticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPVKMRKSGGRNHTGQIQVHGIGGGHKQRYRMIDFLRFRPEHESKPGPFE
EKVIAVRYDPCRSADIALVAGGNRKRWIIATENMKAGDTVLNSDHIGRMA
VAAREGDAHPLGALPVGTLINNVESEPGRGAQYIRAAGTCGVLLRKVNGT
AIIQLPSKRQMQVLETCIATVGRVSNVDHNKRVIGKAGRNRWLGKRPNSG
Ligand information
>4ce4 Chain A (length=1444) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
accaaagcuagcucaacauuuuuuuuaaauaaaauaaaacauucaccuaa
cauuaaaguauaggagauagaaauuuuuauccugacgcuauagagauagu
accguaagggaaagaugaaagaauaaaauaaaaguaaaaaaaagcaaaga
uuaccccuucuaccuuuugcauaaugguuuaaccagaaaaaaucuaacaa
agagaacuuuagcuagauaccccgaaaccagacgagcuacccaugagcag
uuuaaaagaaccaacucaucuauguggcaaaauagugagaagacuuguag
guagaggugaaaagccuaacgagccuggugauagcugguuguccgagaaa
gaauuuuaguucaaccuuaaaaauaccccaaaaauuccaauguauuuuua
agagauagucuaaaaagguacagcuuuuuagaaacggauacaaccuugac
uagagaguaaaucuuaauacacauaaucccaaaaaaacaaacuccuagcc
caauaccggacuaaucuauugaaacauagaagcaauaauguuaauaugag
uaacaagaagccuuucuccucgcacacgcuuacaucaguaacuaauaaua
uacugauaauuaacaaccaauaaaccaaaacaacacuaaaacguuuauua
auuacauuguuaacccaacacaggagugcaccaaggaaagauuaaaagaa
guaaaaggaacucggcaaacacaaaccccgccuguuuaccaaaaacauca
ccucuagcauuacuaguauuagaggcaaugccugcccagugacaccaguu
uaacggccgcgguauucugaccgugcaaagguagcauaaucacuuguucu
ccaaauaaggacuuguaugaauggccacacgaggguuuuacugucucuua
cuuccaaucagugaaauuaaccuucccgugaagaggcgggaauaaaaaaa
uaagacgagaagacccuauggagcuuuaauuaacuauuccaaaaguuaaa
cuuaacauggacuagcaauuucgguuggggugaccucggaguacaaaaaa
cccuccgagugauuuuaaucuagacaaaccagucaaaauaacccaucacu
uauugauccaaaauuuugaucaacggaacaaguuacccuagggauaacag
cgcaauccuguucuagaguuccuaucgacaauaggguuuacgaccucgau
guuggaucaggacacccaaauggugcagccgcuauuaaagguucguuugu
ucaacgauuaaaguccuacgugaucugaguucagaccggagcaauccagg
ucgguuucuaucuauuauaaauuucucccaguacgaaaggacaagagaaa
ugggaccaaccucacaaacgcgucucagagauaauuaaugauuuaaucuu
aaccuaauuaacucauaauaaauccagcccuagaacagggcaca
.........<<<<<.....................<......>.......
..........<<.....>>..............>>.>>>...........
.<<....>>.....................................<<<.
......>>>...<............>..<<<<<........<<<<<.<..
<<....>>...>.>>>>>..<<.<...<<<<.<.....<<<.<<<<<..<
<<<....>>>>...<<<..<<<<........>>>>.>>>....>>>>>.>
>>...<<<.....>>>......>.>>>>......>.>>..<<<<<.....
<<<<....>>>>..<<<<<<<<<<<<.....<<.>>.....>>>>>>>>>
>>.>....<<<<<<<<<......>>>>>>>>>...<<......>>....<
<<<.<<<..................................>>>>>>>..
......>>>>>...<<<<<......>>>>>.........>>>>>.<....
..<<..<<<<..>>>><<<..<<<<........<<<<<....<<....>>
..>>>>>......<<<..<<<<<<<.................>>>>>>>.
......>>>.....<<......>>.>>>>.....>>>..<<<<....<<<
<<<<.<<...............<<<<<<<<..<<<.........>>>...
<<<<<<.............>>>>>>....<<<.<<<..<<<<<....>>>
..>>>>><<<<<<......>>>>>>........<...........<<<<<
.......>>>>>.....>....>>>....>>.>>>>>>......>>.>>>
>>>>.>>>>.>>.....>.....<<<<<........>>>>>.......<<
<.<<<.<<......<<<<.<<<<<<..<<<<..<<<.<<<<.<<<<...>
>>>....>>>>.>>>.>>>>..<<<<.....>>>><<<<<<.........
..>>>>>>.<<<<....<<.<.<<<......>>>.>.>>.....>>>>..
........<<<....>>>............>>>>..>>>>>>.......<
<<....<<<<<<...<<.......>>...>>>>>>.....>>.>......
.<.<<<.<<<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<...
..>>>>>.....>>>>>..>...>>>..>....<<<.<<<....>>>..>
>>....>>..>>>>>>.<<.<<<<<<<.................>>>>>>
><<<<<...............>>>>>.<<<.....<..............
......>....>>>.>>.........<<<<.......>>>>...
Receptor-Ligand Complex Structure
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PDB4ce4 Architecture of the Large Subunit of the Mammalian Mitochondrial Ribosome.
Resolution4.9 Å
Binding residue
(original residue number in PDB)
K81 G84 R85 H87 Q90 I91 Q92 V93 G97 G98 H100 K101 Q102 R103 Y104 Y132 P134 C135 W151 R203 Q206 Y207 I208 R209 A210 A211 G212 T213 L229 P230 S231 R233 M235 H253 N254 I258 G259 K260 A261 G262 N264 W266 R270 S273 G274
Binding residue
(residue number reindexed from 1)
K7 G10 R11 H13 Q16 I17 Q18 V19 G23 G24 H26 K27 Q28 R29 Y30 Y58 P60 C61 W77 R129 Q132 Y133 I134 R135 A136 A137 G138 T139 L155 P156 S157 R159 M161 H179 N180 I184 G185 K186 A187 G188 N190 W192 R196 S199 G200
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0031090 organelle membrane
GO:0043231 intracellular membrane-bounded organelle
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4ce4, PDBe:4ce4, PDBj:4ce4
PDBsum4ce4
PubMed24362565
UniProtF1RRN2

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