Structure of PDB 4by6 Chain D Binding Site BS01

Receptor Information
>4by6 Chain D (length=504) Species: 889517 (Saccharomyces cerevisiae CEN.PK113-7D) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRTEKFYLVFTEWVKLLQRVENNDVITTVFIKQLVEKGVISDTDNLLTFV
KSSLELSVSSFKESDPTDEVFIAIDALGSLIIKLLILQDFKTRRDYINAI
FSVIVLVFAKDHSQEGTTFNERPYFRLFSNILYEWATIRTHNFVRISDSS
TRQELIEFDSVFYNTFSGYLHALQPFAFPGFSFAWVTLLSHRMLLPIMLR
LPNKIGWEKLMLLIIDLFKFLDQYTSKHAVDAVSVVYKGTLRIILGISND
MPSFLIENHYELMNNLPPTYFQLKNVILSAIPKNMTVPNPYDVDLNMEDI
PACKELPEVFFDPVIDLHSLKKPVDNYLRIPSNSLLRTILSAIYKDTYDI
KKGVGYDFLSVDSKLIRAIVLHVGIEAGIEYKRTNAVFNTKSSYYTLLFN
LIQNGSIEMKYQIILSIVEQLRYPNIHTYWFSFVLMNMFKSDEWNDQKLE
VQEIILRNFLKRIIVNKPHTWGVSVFFTQLINNNLLDLPFVQSVPEIKLI
LQQL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4by6 Chain D Residue 3079 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4by6 Structure and RNA-Binding Properties of the not1-not2-not5 Module of the Yeast Ccr4-not Complex
Resolution2.797 Å
Binding residue
(original residue number in PDB)		D1915 D1918 D1931
Binding residue
(residue number reindexed from 1)		D346 D349 D362
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0017148 negative regulation of translation
Cellular Component
GO:0030015 CCR4-NOT core complex

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Biological Process
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Cellular Component
External links
PDB RCSB:4by6, PDBe:4by6, PDBj:4by6
PDBsum4by6
PubMed24121231
UniProtP25655|NOT1_YEAST General negative regulator of transcription subunit 1 (Gene Name=CDC39)

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