Structure of PDB 4av1 Chain D Binding Site BS01

Receptor Information
>4av1 Chain D (length=95) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRW
YHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGV
Ligand information
Receptor-Ligand Complex Structure
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PDB4av1 The Zinc-Finger Domains of Parp1 Cooperate to Recognise DNA Strand-Breaks
Resolution3.1 Å
Binding residue
(original residue number in PDB)		K119 S120 T124 R138 D145 K148 L151 I154
Binding residue
(residue number reindexed from 1)		K12 S13 T17 R31 D38 K41 L44 I47
Enzymatic activity
Enzyme Commision number 2.4.2.-
2.4.2.30: NAD(+) ADP-ribosyltransferase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:4av1, PDBe:4av1, PDBj:4av1
PDBsum4av1
PubMed22683995
UniProtP09874|PARP1_HUMAN Poly [ADP-ribose] polymerase 1 (Gene Name=PARP1)

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