Structure of PDB 4a25 Chain D Binding Site BS01

Receptor Information
>4a25 Chain D (length=166) Species: 131568 (Kineococcus radiotolerans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TIHDVQTTGLTQDAVTGFDASSRLNAGLQEVLVDLTALHLQGKQAHWNIV
GENWRDLHLQLDTLVEAARGFSDDVAERMRAVGGVPDARPQTVAASRIGD
VGPDEIDTRACVEAIVALVRHTVDTIRRVHDPIDAEDPASADLLHAITLE
LEKQAWMIGSENRSPR
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain4a25 Chain D Residue 1169 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4a25 Kineococcus Radiotolerans Dps Forms a Heteronuclear Mn-Fe Ferroxidase Center that May Explain the Mn-Dependent Protection Against Oxidative Stress.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		D75 E79
Binding residue
(residue number reindexed from 1)		D73 E77
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008199 ferric iron binding
GO:0016722 oxidoreductase activity, acting on metal ions
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4a25, PDBe:4a25, PDBj:4a25
PDBsum4a25
PubMed23396000
UniProtA6WG04

[Back to BioLiP]