Structure of PDB 3zla Chain D Binding Site BS01

Receptor Information
>3zla Chain D (length=228) Species: 35304 (Bunyamwera virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSMIELEFHDVTFDPEVAYANFKRVHTTGLSYDHIRIFYIKGREIKTSLA
KRSEWEVTLNLGGWKITVYNTNFPGNRNNPVPDDGLTLHRLSGFLARYLL
EKMLKVSEPEKLIIKSKIINPLAEKNGITWNDGEEVYLSFFPGSEMFLGT
FRFYPLAIGIYKVQRKEMEPKYLEKTMRQRYMGLEAATWTVSKLTEVQSA
LTVVSSLGWKKTNVSAAARDFLAKFGIN
Ligand information
>3zla Chain I (length=44) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
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PDB3zla Nucleocapsid Protein Structures from Orthobunyaviruses Reveal Insight Into Ribonucleoprotein Architecture and RNA Polymerization.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		I44 R47 K50 T75 R81 N82 L126 K175 Y176 K179 R182 Q183 R184 N217
Binding residue
(residue number reindexed from 1)		I40 R43 K46 T71 R77 N78 L122 K171 Y172 K175 R178 Q179 R180 N213
Binding affinityPDBbind-CN: Kd=62.9nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0039657 symbiont-mediated suppression of host gene expression
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3zla, PDBe:3zla, PDBj:3zla
PDBsum3zla
PubMed23595147
UniProtP16495|NCAP_BUNYW Nucleoprotein (Gene Name=N)

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