Structure of PDB 3zjc Chain D Binding Site BS01

Receptor Information
>3zjc Chain D (length=223) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASRDLLVVD
TPGLFDTKESLDTTCKEISRCIISSCPGPHAIVLVLQLGRYTEEEQKTVA
LIKAVFGKSAMKHMVILFTRKEELEGQSFHDFIADADVGLKSIVKECGNR
CCAFSNTSKAEKESQVQELVELIEKMVGAYFSDDIYKDTEERLKQRFKDV
FNRIWKMLSEIWHRFLSKCKFYS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3zjc Chain D Residue 1300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3zjc Structural Insights Into the Mechanism of Gtpase Activation in the Gimap Family.
Resolution3.15 Å
Binding residue
(original residue number in PDB)
S22 T44
Binding residue
(residue number reindexed from 1)
S14 T36
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0046039 GTP metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005811 lipid droplet

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3zjc, PDBe:3zjc, PDBj:3zjc
PDBsum3zjc
PubMed23454188
UniProtQ8NHV1|GIMA7_HUMAN GTPase IMAP family member 7 (Gene Name=GIMAP7)

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