Structure of PDB 3wvi Chain D Binding Site BS01

Receptor Information
>3wvi Chain D (length=298) Species: 71421 (Haemophilus influenzae Rd KW20) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSALEKLLSLIENLTNQEFKQATNSLISFIYKLNRNEVIELVRSIGILPE
AIKPSSTQEKLFSKAGDIVLAKAFQLLNLNSKPLEQRGNAGDVIALSKEF
NYGLVADAKSFRLSRTAKNQKDFKVKALSEWREDKDYAVLTAPFFQYPTT
KSQIFKQSLDENVLLFSWEHLAILLQLDLEETNIFSFEQLWNFPKKQSKK
TSVSDAENNFMRDFNKYFMDLFKIDKDTLNQLLQKEINFIEERSLIEKEY
WKKQINIIKNFTREEAIEALLKDINMSSKIETIDSFIKGIKSNDRLYL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3wvi Analysis of the HindIII-catalyzed reaction by time-resolved crystallography
Resolution2.55 Å
Binding residue
(original residue number in PDB)		L49 E60 S64 D93 D108 S111 F112 R113 R116 T117 A118 D123 K125 W132
Binding residue
(residue number reindexed from 1)		L48 E59 S63 D92 D107 S110 F111 R112 R115 T116 A117 D122 K124 W131
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3wvi, PDBe:3wvi, PDBj:3wvi
PDBsum3wvi
PubMed25664735
UniProtP43870|T2D3_HAEIN Type II restriction enzyme HindIII (Gene Name=hindIIIR)

[Back to BioLiP]