Structure of PDB 3w1k Chain D Binding Site BS01

Receptor Information
>3w1k Chain D (length=452) Species: 224324 (Aquifex aeolicus VF5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKSLLRQIPQISKVVEIFAKAYPEIYVVKAAREVAEKYRKEIIEGARADL
NGFLEDVERKIKSLMKPNIKRVINATGVVINTNLGRAPLSKDVINFISEI
ANGYSNLEYNLEEGKRGSRIAHIEKYLNELTGAESSFVVNNNAGAVFLVL
NTLAEGKEVIISRGELVEIGGSFRIPDIMKKSGAILREVGTTNKTKVSDY
EGAINQNTALLMKVHKSNFYMEGFVEEVKLEDLVKLGHKYGIPTYYDAGS
GLLINLKEFGISVDEPNFRDCISLGIDLVSGSGDKLLGGPQAGIIVGKKN
LIEKIKKNPIARALRIDKLTLSGLEMTLKLYFEKRYEDIPVIRMLTQDEK
ALRQKAKRLEKLLKDIPGLKISVIKDKAKPGGGSLPELELPTYCVAIRHD
RLSSQELSRRLRLAEPPIVCRIREDQLLFDMRTVFHEDLKTIKKTLQELL
SI
Ligand information
>3w1k Chain H (length=92) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggaguagauaggcgcuggugugccuccuagacuucaaaucuacggucuc
gcuauuuaagcgagagguggguucgauucccacauacucccg
<<<<<<<...<<<<<......>>>>><<<<<<.......>>>>.>><<<<
<<<.....>>>>>>>.<<<<<.......>>>>>.>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3w1k Decameric SelA-tRNA(Sec) ring structure reveals mechanism of bacterial selenocysteine formation
Resolution7.5 Å
Binding residue
(original residue number in PDB)		K2 L5 R6 I8 P9 Q10 I11 S12 E16 V28 R32 R39
Binding residue
(residue number reindexed from 1)		K2 L5 R6 I8 P9 Q10 I11 S12 E16 V28 R32 R39
Binding affinityPDBbind-CN: Kd=75nM
Enzymatic activity
Enzyme Commision number 2.9.1.1: L-seryl-tRNA(Sec) selenium transferase.
Gene Ontology
Molecular Function
GO:0004125 L-seryl-tRNA(Sec) selenium transferase activity
GO:0016740 transferase activity
GO:0042802 identical protein binding
Biological Process
GO:0001514 selenocysteine incorporation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3w1k, PDBe:3w1k, PDBj:3w1k
PDBsum3w1k
PubMed23559248
UniProtO67140|SELA_AQUAE L-seryl-tRNA(Sec) selenium transferase (Gene Name=selA)

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