Structure of PDB 3ueo Chain D Binding Site BS01
Receptor Information
>3ueo Chain D (length=186) Species:
9606
(Homo sapiens) [
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GLFSQKSFLVLGFSNENESNIANIIKENAGKIMVADYAVVPLLGCEVEAT
VGEVVTNTWLVTCIDYQTLFDPKSNPLFTPVPVMTGMTPLEDCVISFSQC
AGAEKESLTFLANLLGASVQEYFVRKSNAKKGMFASTHLILKERGGSKYE
AAKKWNLPAVTIAWLLETARTGKRADESHFLIENST
Ligand information
>3ueo Chain E (length=10) Species:
9606
(Homo sapiens) [
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FIDSDTDVEE
Receptor-Ligand Complex Structure
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PDB
3ueo
Structural insights into recognition of MDC1 by TopBP1 in DNA replication checkpoint control.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
S654 Q655 Y678 F679 K687 E699 S703 K704 W711
Binding residue
(residue number reindexed from 1)
S98 Q99 Y122 F123 K131 E143 S147 K148 W155
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3ueo
,
PDBe:3ueo
,
PDBj:3ueo
PDBsum
3ueo
PubMed
23891287
UniProt
Q92547
|TOPB1_HUMAN DNA topoisomerase 2-binding protein 1 (Gene Name=TOPBP1)
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