Structure of PDB 3u5o Chain D Binding Site BS01

Receptor Information
>3u5o Chain D (length=187) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCR
DIGKPEVEYDCDNLQHSLSPVDQRKCERLLLYLYCHELSIEFQEPVPASI
PNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNE
MMKVVQVYASEVAQAGKAVALYFEDKLTEIYSDRTFA
Ligand information
>3u5o Chain L (length=20) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ARTKQTARKSTGGKAPRKQL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3u5o A poised chromatin platform for TGF-beta access to master regulators
Resolution2.7 Å
Binding residue
(original residue number in PDB)		D884 N886 D888 W889 Q894 N895 G896 G897 D898 L899 C901 H910 G924 I980 E981 E1061 V1062
Binding residue
(residue number reindexed from 1)		D2 N4 D6 W7 Q12 N13 G14 G15 D16 L17 C19 H28 G42 I90 E91 E161 V162
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:3u5o, PDBe:3u5o, PDBj:3u5o
PDBsum3u5o
PubMed22196728
UniProtQ9UPN9|TRI33_HUMAN E3 ubiquitin-protein ligase TRIM33 (Gene Name=TRIM33)

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