Structure of PDB 3r85 Chain D Binding Site BS01
Receptor Information
>3r85 Chain D (length=139) Species:
9606
(Homo sapiens) [
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QSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDL
TSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKE
MQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGN
Ligand information
>3r85 Chain H (length=19) Species:
9606
(Homo sapiens) [
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QEQLLTLASILREDGKVFD
Receptor-Ligand Complex Structure
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PDB
3r85
Structural changes in the BH3 domain of SOUL protein upon interaction with the anti-apoptotic protein Bcl-xL.
Resolution
1.95 Å
Binding residue
(original residue number in PDB)
F97 Y101 A104 F105 L108 Q111 V126 E129 L130 D133 N136 G138 R139
Binding residue
(residue number reindexed from 1)
F39 Y43 A46 F47 L50 Q53 V68 E71 L72 D75 N78 G80 R81
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0042981
regulation of apoptotic process
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Biological Process
External links
PDB
RCSB:3r85
,
PDBe:3r85
,
PDBj:3r85
PDBsum
3r85
PubMed
21639858
UniProt
Q07817
|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)
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