Structure of PDB 3r85 Chain D Binding Site BS01

Receptor Information
>3r85 Chain D (length=139) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDL
TSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKE
MQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3r85 Structural changes in the BH3 domain of SOUL protein upon interaction with the anti-apoptotic protein Bcl-xL.
Resolution1.95 Å
Binding residue
(original residue number in PDB)
F97 Y101 A104 F105 L108 Q111 V126 E129 L130 D133 N136 G138 R139
Binding residue
(residue number reindexed from 1)
F39 Y43 A46 F47 L50 Q53 V68 E71 L72 D75 N78 G80 R81
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

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Biological Process
External links
PDB RCSB:3r85, PDBe:3r85, PDBj:3r85
PDBsum3r85
PubMed21639858
UniProtQ07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

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