Structure of PDB 3r7n Chain D Binding Site BS01

Receptor Information
>3r7n Chain D (length=97) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KMRLPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDMHVA
DMLVKVNALIKDREGYAPGTEFHRCKEMSEYCSTLCRHLYLFPGHPP
Ligand information
Receptor-Ligand Complex Structure
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PDB3r7n Structural and enzymatic insights into caspase-2 protein substrate recognition and catalysis.
Resolution2.33 Å
Binding residue
(original residue number in PDB)		A376 M377 R378 N379 T380 W385 G419 Y420 F426
Binding residue
(residue number reindexed from 1)		A22 M23 R24 N25 T26 W31 G65 Y66 F72
Enzymatic activity
Enzyme Commision number 3.4.22.55: caspase-2.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3r7n, PDBe:3r7n, PDBj:3r7n
PDBsum3r7n
PubMed21828056
UniProtP42575|CASP2_HUMAN Caspase-2 (Gene Name=CASP2)

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