Structure of PDB 3pgd Chain D Binding Site BS01

Receptor Information
>3pgd Chain D (length=179) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFA
SFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP
NVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLP
FLPSTEDVYDCRVEHWGLDEPLLKHWEFD
Ligand information
Receptor-Ligand Complex Structure
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PDB3pgd Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Resolution2.72 Å
Binding residue
(original residue number in PDB)
Q9 S53 F54 G58 N62 N69 M73
Binding residue
(residue number reindexed from 1)
Q7 S51 F52 G56 N60 N67 M71
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process

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Cellular Component
External links
PDB RCSB:3pgd, PDBe:3pgd, PDBj:3pgd
PDBsum3pgd
PubMed21115828
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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