Structure of PDB 3pcs Chain D Binding Site BS01

Receptor Information

>3pcs Chain D (length=348) Species: 83334 (Escherichia coli O157:H7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KKSWDEMSCAEKLFKVLSFGLWNPTYSRSERQSFQELLTVLEPVYPLPNE
LGRVSARFSDGSSLRISVTNSELVEAEIRTANNEKITVLLESNEQNRLLQ
SLPIDRHMPYIQVHRALLTDTTSMRNLLGFTSKLSTTLIPHNAQTDPLSG
PTPFSSIFMDTCRGLGNAKLSLNGVDIPANAQKLLRDALGLKDTHSSPTR
NVIDHGISRHDAEQIARESSGSDKQKAEVVEFLCHPEAATAICSAFYQSF
NVPALTLTHERISKASEYNAERDTPNACINISISQSSDGNIYVTSHTGVL
IMAPEDRPNEMGMLTNRTSYEVPQGVKCIIDEMVSALQPRYAASETYL

Ligand information

>3pcs Chain H (length=13) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

AVLDVLKFYDSNT

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3pcs The assembly of a GTPase-kinase signalling complex by a bacterial catalytic scaffold.
Resolution	2.86 Å
Binding residue (original residue number in PDB)	R170 N212 Q293 L300 P322 N323 A324 I326 V346
Binding residue (residue number reindexed from 1)	R125 N167 Q248 L255 P275 N276 A277 I279 V299

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0004197	cysteine-type endopeptidase activity

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Molecular Function

External links

PDB	RCSB:3pcs, PDBe:3pcs, PDBj:3pcs
PDBsum	3pcs
PubMed	21170023
UniProt	Q7DB50

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