Structure of PDB 3nw3 Chain D Binding Site BS01

Receptor Information
>3nw3 Chain D (length=171) Species: 9838 (Camelus dromedarius) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDPPACGSIVPRREWRALASECRERLTRPVRYVVVSHTAGSHCDTPASCA
QQAQNVQSYHVRNLGWCDVGYNFLIGEDGLVYEGRGWNIKGAHAGPTWNP
ISIGISFMGNYMNRVPPPRALRAAQNLLACGVALGALRSNYEVKGHRDVQ
PTLSPGDRLYEIIQTWSHYRA
Ligand information
Ligand IDDGN
InChIInChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m1/s1
InChIKeyZDXPYRJPNDTMRX-GSVOUGTGSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(CC(=O)N)C(C(=O)O)N
ACDLabs 10.04O=C(N)CCC(N)C(=O)O
OpenEye OEToolkits 1.5.0C(CC(=O)N)[C@H](C(=O)O)N
CACTVS 3.341N[CH](CCC(N)=O)C(O)=O
CACTVS 3.341N[C@H](CCC(N)=O)C(O)=O
FormulaC5 H10 N2 O3
NameD-GLUTAMINE
ChEMBLCHEMBL1232207
DrugBankDB02174
ZINCZINC000001532609
PDB chain3nw3 Chain D Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3nw3 Multiligand specificity of pathogen-associated molecular pattern-binding site in peptidoglycan recognition protein
Resolution2.5 Å
Binding residue
(original residue number in PDB)		W98 D148 V149
Binding residue
(residue number reindexed from 1)		W98 D148 V149
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) Y71 T152
Catalytic site (residue number reindexed from 1) Y71 T152
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity
GO:0016019 peptidoglycan immune receptor activity
GO:0042834 peptidoglycan binding
Biological Process
GO:0001818 negative regulation of cytokine production
GO:0009253 peptidoglycan catabolic process
GO:0016045 detection of bacterium
GO:0042742 defense response to bacterium
GO:0045087 innate immune response
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3nw3, PDBe:3nw3, PDBj:3nw3
PDBsum3nw3
PubMed21784863
UniProtQ9GK12|PGRP1_CAMDR Peptidoglycan recognition protein 1 (Gene Name=PGLYRP1)

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