Structure of PDB 3nik Chain D Binding Site BS01

Receptor Information
>3nik Chain D (length=82) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSVHKHTGRNCGRKFKIGEPLYRCHECGCDDTCVLCIHCFNPKDHVNHHV
CTDICTEFTSGICDCGDEEAWNSPLHCKAEEQ
Ligand information
Receptor-Ligand Complex Structure
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PDB3nik Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases
Resolution1.85 Å
Binding residue
(original residue number in PDB)		L133 R135 T144 C145 T171 G173 I174 D176 A182
Binding residue
(residue number reindexed from 1)		L21 R23 T32 C33 T59 G61 I62 D64 A70
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway

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Molecular Function
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Biological Process
External links
PDB RCSB:3nik, PDBe:3nik, PDBj:3nik
PDBsum3nik
PubMed20835240
UniProtP19812|UBR1_YEAST E3 ubiquitin-protein ligase UBR1 (Gene Name=UBR1)

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