Structure of PDB 3m1y Chain D Binding Site BS01

Receptor Information

>3m1y Chain D (length=206) Species: 210 (Helicobacter pylori)

SLQKLAVFDFDSTLVNAETIESLARAWGVFDEVKTITLKAMNETDFHKSL
ILRVSKLKNMPLKLAKEVCESLPLFEGALELVSALKEKNYKVVCFSGGFD
LATNHYRDLLHLDAAFSNTLIVENDALNGLVTGHMMFSHSKGEMLLVLQR
LLNISKTNTLVVGDGANDLSMFKHAHIKIAFNAKEVLKQHATHCINEPDL
ALIKPL

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 3m1y Chain D Residue 300

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3m1y Crystal Structure of a Phosphoserine phosphatase (SerB) from Helicobacter pylori
• Resolution: 2.4 Å
• Binding residue (original residue number in PDB): D8 D10 D164
• Binding residue (residue number reindexed from 1): D9 D11 D164
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): D8 F9 D10 G97 K141 D168
• Catalytic site (residue number reindexed from 1): D9 F10 D11 G97 K141 D168
• Enzyme Commision number: 3.1.3.3: phosphoserine phosphatase.

Gene Ontology

Molecular Function

• GO:0000287 magnesium ion binding
• GO:0016787 hydrolase activity
• GO:0036424 L-phosphoserine phosphatase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006564 L-serine biosynthetic process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:3m1y, PDBe:3m1y, PDBj:3m1y
• PDBsum: 3m1y
• UniProt: O25367