Structure of PDB 3k0j Chain D Binding Site BS01

Receptor Information
>3k0j Chain D (length=82) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRPNHTIYINNLNEKIKKDELKKSLHAIFSRFGQILDILVSRSMRGQAFV
IFKEVSSATNALRSMQGFPFYDKPMRIQYAKT
Ligand information
>3k0j Chain E (length=87) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcgacucggggugcccuccauugcacuccggaggcugagaaauacccgua
ucaccugaucuggauaaugccagcguagggaagucgc
<<<<<<<<<<..<<<.<<<..........>>>>>>.........>>>>..
...<<<...<<<<......>>>>...>>>..>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3k0j Thermodynamic analysis of ligand binding and ligand binding-induced tertiary structure formation by the thiamine pyrophosphate riboswitch.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		E525 K528
Binding residue
(residue number reindexed from 1)		E20 K23
Binding affinityPDBbind-CN: Kd=8.65nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:3k0j, PDBe:3k0j, PDBj:3k0j
PDBsum3k0j
PubMed19948769
UniProtP09012|SNRPA_HUMAN U1 small nuclear ribonucleoprotein A (Gene Name=SNRPA)

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