Structure of PDB 3jbn Chain D Binding Site BS01

Receptor Information
>3jbn Chain D (length=157) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PISKKRKFINDGVFQAELNEFLARILAEDGYSGVEVRIRELTSLVQKRFF
LCAMAQAESLRYKLLKGLAVRRACYGVLRHIMESGAKGCEVIVSGKLRAQ
RAKSMKFRDGYLISTGEPSKRFVNTATRSAQLKQGVLGIKVKIMLPTSIL
PDNISVL
Ligand information
>3jbn Chain A (length=1608) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaccugguugaucuugccaguagucauaugcuugucucaaagauuaagcc
augcaagugaaaguauauauauauauauguagaaacugcgaacggcucau
uaaaacaguuauagucuacuugacauuuauaaggauaacuacggaaaagc
uguagcuaauacuugcauuauccuuuuggauaaguauuuguuagaaggaa
uuauaacaaagaaguaacacguaaaguguguaucaaucgaguuucugacc
uaucagcuuuugauguuaggguauuggccuaacauggcuaugacggguaa
cggggaauuagaguucgauuccggagagggagccugagaaauagcuacca
caucuaaggaaggcagcaggcgcguaaauuacccaauucuaaagaagaga
gguagugacaagaaauaacaaugcaagguuuguauuggaauggugggaau
uuaaaaccuucccagaguaacaauuggagggcaagucuggugccagcagc
cgcgguaauuccagcuccaauagcguauauuaaaauuguugcaguuaaaa
cgcucguaguugaauuucaaagaaucauucuuuuuaaaauccgauuuugu
uacuuugaguaaauuagaguguucaaagcaaacaguuaaagcauuguguu
ugaauacuauagcauggaauaacaaaauugaacaagcuaaaauuuuuugu
ucuuauuuuggcuuaguuacgauuaauaggaguagcuuggggacauucgu
auucagaugucagaggugaaauucuuagauuuucuggagacgaacaacug
cgaaagcauuugucuaaaauacuuccauuaaucaagaacgaaaguuaagg
gagugaagacgaucagauaccgucguaaucuuaaccauaaacuaugccga
cuagguguuggaugaagugcuuccuucaguaccuuaugagaaaucaaagu
cuuuggguucuggggcgaguauucgcgcaagcgagaaaguuaaaagaauu
gacggaagggcaccaccaggcguggagcuugcggcuuaauuugacucaac
acggggaaacucacuaguuuaagacauuggauggugaugcauggccguuu
uuaguucgugaaugauuugucugguuaauuccgauaacgaacgagaucuu
aaccugcuaauuagcggcgaguacacuguacuugcugcuucuuagaggaa
cauugugugucuaacacaaggaaguuuaaggcaacaacaggucugugaug
uccuuagaugaacuaggcugcacgcgugcuacacugauauauauaacgag
uaaaauaugcuugcauacuuuuccuccgccgaaaggcguagguaaucuuu
aucaauauauaucgugauggggauagauuauugcaauuauuaaucuugaa
cgaggaaugccuaguaagcaugauucaucagauugugcuaacuacguccc
ugcccuuuguacacaccgcccgucgcuccuaccgauugaaagauaugaug
aauuguuuggacaagaaaaauuuuuucuggaaaaaccguaaauccuaucu
uuuaaaggaaggagaagucguaacaagguuuccguaggugaaccugcgga
aggaucau
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.>.>>>>>>>.......<<<.....>>>....>>>>..>>>>..>>>.<<
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<<<.<<<<....>>>>....>>>.>>.<<.<<<..........>>>.>>.
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>>>..>....>>>.....<<<<<<<<...>>>>>>>>......<<<<<<.
........>>>>>>.........<<<<<((......<<<<.....<<..)
)>>.......>>>>.>>>>>..>>>>>>>>>>.........<<<((....
.<.<<...<<<.<<....<<<<.<....>.>>>>..<<<......>>><<
<<<<.<<.......<<...<.......>.<<<<.......<<<.>>>>>>
>...>>......>>.>>..>>>>.....<.<<<.<<.<.<<<.<......
....>.>>>.>.>>.>>>..>.>>....<<<<<<..<<..<<<<<..<<<
.<<<<<<.<...<<<......>>>......>.>>>>>>.>>>......<<
<....>>>..>>>>>.>>.>>>.>>>...>>>...>>.>....<<<<<<.
..<<...<<<<.........>>>>...>>>>>>>>..........<<<.<
<.<<<<<<<<<<.<<<<..>>>>.>>>>>>>>>>...<<..))>>...>>
.....>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<
<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<<<......<<.......
.>>..........<<<<<<<....<<.>>...<<.<<<..<<<<<<<<..
...<<<<<<<<<...>>>...<<<......>>>...>>>>>>....<<<<
<.<<<.<<<...<<<<<<<<<<<<...>>>>>>>>>>>>...>>>>>>..
..<<<<<<.....>>>>>>.......>>>>>.....>>.>>>...>.>>>
>>>>.....>>>>>>>...>>.>>>>.>>>.....<<<<<<<<.....<<
.<<<.<<<<<..>>>>>.>>.><<<.<<<<....>>>>.>>>....>>..
.....>>>>>>>>......<....<<<<<<..........>>>>>>....
>.....>>>>>>....<<<<<<<<.......>>>>>>>>......>>...
>>>>>>>>>>.>>....<..<<.<.<<<<<.<<....<<.<<<<<.<<<.
.<<.<<<<...<<.<<<<<.>>>.>>.>>...>>>>.>>..>>>.>>>>>
>.>...>>.>>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>
>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3jbn Dynamical features of the Plasmodium falciparum ribosome during translation.
Resolution4.7 Å
Binding residue
(original residue number in PDB)		P4 I5 S6 K7 K8 R9 R27 S140 G141 K142 R144 Q146 R147 A148 K152 R154 Y157 I159 S160 T161 E163 P164 K166 Q177 V182 G184 K186 D211
Binding residue
(residue number reindexed from 1)		P1 I2 S3 K4 K5 R6 R24 S94 G95 K96 R98 Q100 R101 A102 K106 R108 Y111 I113 S114 T115 E117 P118 K120 Q131 V136 G138 K140 D152
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3jbn, PDBe:3jbn, PDBj:3jbn
PDBsum3jbn
PubMed26432834
UniProtQ8IKH8

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