Structure of PDB 3ie1 Chain D Binding Site BS01

Receptor Information

>3ie1 Chain D (length=431) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MRIVPFGAAREVTGSAHLLLAGGRRVLLDCGMFQGKEEARNHAPFGFDPK
EVDAVLLTHAHLDHVGRLPKLFREGYRGPVYATRATVLLMEIVLEDALKV
MDEPFFGPEDVEEALGHLRPLEYGEWLRLGALSLAFGQAGHLPGSAFVVA
QGEGRTLVYSGDLGNREKDVLPDPSLPPLADLVLAEGTYGDRPHRPYRET
VREFLEILEKTLSQGGKVLIPTFAVERAQEILYVLYTHGHRLPRAPIYLD
SPMAGRVLSLYPRLVRYFSEEVQAHFLQGKNPFRPAGLEVVEHTEASKAL
NRAPGPMVVLAGSGMLAGGRILHHLKHGLSDPRNALVFVGYQPQGGLGAE
IIARPPAVRILGEEVPLRASVHTLGGFSGAAGQDELLDWLQGEPRVVLVH
GEEEKLLALGKLLALRGQEVSLARFGEGVPV

Ligand information

>3ie1 Chain H (length=4) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

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Receptor-Ligand Complex Structure

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Structure summary

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PDB	3ie1 Crystal structure of H380A mutant TTHA0252 from Thermus thermophilus HB8 complexed with RNA
Resolution	2.85 Å
Binding residue (original residue number in PDB)	Q34 H61 L62 D63 D96 A97 V100 M101 H141 D162 F223 V225 P252 M253 S313 M315 R320 H400
Binding residue (residue number reindexed from 1)	Q34 H61 L62 D63 D96 A97 V100 M101 H141 D162 F223 V225 P252 M253 S313 M315 R320 H400

Enzymatic activity

Enzyme Commision number

3.1.-.-

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0004519	endonuclease activity
GO:0004521	RNA endonuclease activity
GO:0046872	metal ion binding

	Biological Process
GO:0006364	rRNA processing

	Cellular Component
GO:0005737	cytoplasm

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External links

PDB	RCSB:3ie1, PDBe:3ie1, PDBj:3ie1
PDBsum	3ie1
PubMed
UniProt	Q5SLP1\|RNSE_THET8 Ribonuclease TTHA0252 (Gene Name=TTHA0252)

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