Structure of PDB 3hym Chain D Binding Site BS01

Receptor Information
>3hym Chain D (length=301) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ENLDVVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVEL
NKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARRYLSKATT
LEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEY
GLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDA
LEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQN
ASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIEMYIG
D
Ligand information
>3hym Chain C (length=23) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
MLRRKPTRLELKLDDIEEFENIR
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3hym Insights into anaphase promoting complex TPR subdomain assembly from a CDC26-APC6 structure.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		Y242 Y243 C245 A345 L369 Y373 L376 E377 D401 F403 H406 E407 E445 P446 N449 N450 H453 R456 K457 N478 S480 Y487 S490 L491 F514 M518 M525
Binding residue
(residue number reindexed from 1)		Y14 Y15 C17 A117 L141 Y145 L148 E149 D173 F175 H178 E179 E217 P218 N221 N222 H225 R228 K229 N250 S252 Y259 S262 L263 F286 M290 M297
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3hym, PDBe:3hym, PDBj:3hym
PDBsum3hym
PubMed19668213
UniProtQ13042|CDC16_HUMAN Cell division cycle protein 16 homolog (Gene Name=CDC16)

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