Structure of PDB 3hpj Chain D Binding Site BS01
Receptor Information
>3hpj Chain D (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>3hpj Chain F (length=9) Species:
9606
(Homo sapiens) [
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RMFPNAPYL
Receptor-Ligand Complex Structure
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PDB
3hpj
Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A*0201: Implications for WT1-based cancer therapeutics.
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
Y7 M45 E58 E63 K66 H70 T73 V76 D77 Y84 R97 Y99 T143 W147 Q155 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 M45 E58 E63 K66 H70 T73 V76 D77 Y84 R97 Y99 T143 W147 Q155 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3hpj
,
PDBe:3hpj
,
PDBj:3hpj
PDBsum
3hpj
PubMed
20619457
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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