Structure of PDB 3gut Chain D Binding Site BS01
Receptor Information
>3gut Chain D (length=312) Species:
9606
(Homo sapiens) [
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GPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYV
GPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGVCTVTAGPKDMVVGFANLG
ILHVTKKKVFETLEARMTEACIRGYNPGLLVHSDLAYLQAEGGGDRQLTD
REKEIIRQAAVQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIY
DSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEEN
GGVWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLE
TSEPKPFLYYPE
Ligand information
>3gut Chain X (length=26) [
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agggactttccgctggggactttcca
Receptor-Ligand Complex Structure
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PDB
3gut
Structural basis of HIV-1 activation by NF-kappaB--a higher-order complex of p50:RelA bound to the HIV-1 LTR.
Resolution
3.59 Å
Binding residue
(original residue number in PDB)
R356 S363 H364 G365
Binding residue
(residue number reindexed from 1)
R18 S25 H26 G27
Binding affinity
PDBbind-CN
: Kd=1.5nM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003700
DNA-binding transcription factor activity
Biological Process
GO:0006355
regulation of DNA-templated transcription
Cellular Component
GO:0005737
cytoplasm
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:3gut
,
PDBe:3gut
,
PDBj:3gut
PDBsum
3gut
PubMed
19683540
UniProt
P19838
|NFKB1_HUMAN Nuclear factor NF-kappa-B p105 subunit (Gene Name=NFKB1)
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