Structure of PDB 3gjq Chain D Binding Site BS01

Receptor Information
>3gjq Chain D (length=93) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMH
ILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
Ligand information
Receptor-Ligand Complex Structure
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PDB3gjq Caspase-3 binds diverse P4 residues in peptides as revealed by crystallography and structural modeling.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		S205 W206 R207 S209 F250 F256
Binding residue
(residue number reindexed from 1)		S21 W22 R23 S25 F66 F72
Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3gjq, PDBe:3gjq, PDBj:3gjq
PDBsum3gjq
PubMed19283487
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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