Structure of PDB 3fv3 Chain D Binding Site BS01

Receptor Information
>3fv3 Chain D (length=338) Species: 5480 (Candida parapsilosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DSISLSLINEGPSYASKVSVGSNKQQTVIIDTGSSDFWVVDSNAQCGKGV
DCKSSGTFTPSSSSSYKNLGAAFTIRYGDGSTSQGTWGKDTVTINGVSIT
GQQIADVTQTSVDQGILGIGYTSNEAVYDTSGRQTTPNYDNVPVTLKKQG
KIRTNAYSLYLNSPSAETGTIIFGGVDNAKYSGKLVAEQVTSSQALTISL
ASVNLKGSSFSFGDGALLDSGTTLTYFPSDFAAQLADKAGARLVQVARDQ
YLYFIDCNTDTSGTTVFNFGNGAKITVPNTEYVYQNGDGTCLWGIQPSDD
TILGDNFLRHAYLLYNLDANTISIAQVKYTTDSSISAV
Ligand information
>3fv3 Chain L (length=6) Species: 285516 (Streptomyces argenteolus subsp. toyonakensis) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
VVVLAL
Receptor-Ligand Complex Structure
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PDB3fv3 The crystal structure of the secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A
Resolution1.85 Å
Binding residue
(original residue number in PDB)		D32 G34 Y78 G79 D80 D220 G222 T223 T224 Y227 Y285 D301 I303
Binding residue
(residue number reindexed from 1)		D31 G33 Y77 G78 D79 D219 G221 T222 T223 Y226 Y284 D300 I302
Enzymatic activity
Enzyme Commision number 3.4.23.24: candidapepsin.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region

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Biological Process
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Cellular Component
External links
PDB RCSB:3fv3, PDBe:3fv3, PDBj:3fv3
PDBsum3fv3
PubMed19401235
UniProtP32951|CARP1_CANPA Candidapepsin-1 (Gene Name=SAPP1)

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