Structure of PDB 3erc Chain D Binding Site BS01

Receptor Information
>3erc Chain D (length=445) Species: 10254 (Vaccinia virus WR) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NITLKIIETYLGRVPSVNEYHMLKSQARNIQKITVFNKDIFVSLVKKNKK
RFFSDVNTSASEIKDRILSYFSKQTQTYNIGKLFTIIELQSVLVTTYTDI
LGVLTINVTSMEELARDMLNSMNVAVVSSLVKNVNKLMEEYLRRHNKSCI
CYGSYSLYLINPNIRYGDIDILQTNSRTFLIDLAFLIKFITGNNIILSKI
PYLRNYMVIKDENDNHIIDSFNIRQDTMNVVPKIFIDNIYIVDPTFQLLN
MIKMFSQIDRLEDLSKDPEKFNARMATMLEYVRYTHGIVFDGKRNNMPMK
CIIDENNRIVTVTTKDYFSFKKCLVYLDENVLSSDILDLNADTSCDFESV
TNSVYLIHDNIMYTYFSNTILLSDKGKVHEISARGLCAHILLYQMLTSGE
YKQCLSDLLNSMMNRDKIPIYSHTERDKKPGRHGFINIEKDIIVF
Ligand information
Receptor-Ligand Complex Structure
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PDB3erc Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase
Resolution3.21 Å
Binding residue
(original residue number in PDB)
Y236 L237 F255 H467
Binding residue
(residue number reindexed from 1)
Y202 L203 F221 H433
Enzymatic activity
Enzyme Commision number 2.7.7.19: polynucleotide adenylyltransferase.
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016740 transferase activity
GO:0046872 metal ion binding
GO:1990817 poly(A) RNA polymerase activity
Biological Process
GO:0006397 mRNA processing

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Molecular Function

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Biological Process
External links
PDB RCSB:3erc, PDBe:3erc, PDBj:3erc
PDBsum3erc
PubMed19446524
UniProtP23371|PAP1_VACCW Poly(A) polymerase catalytic subunit (Gene Name=OPG063)

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