Structure of PDB 2znv Chain D Binding Site BS01
Receptor Information
>2znv Chain D (length=172) Species:
9606
(Homo sapiens) [
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GLRCVVLPEDLCHKFLQLAESNTVRGIATCGILCGKLTHNEFTITHVIVP
KQSAGPDYCDMENVEELFNVQDQHDLLTLGWIHTHPTQTAFLSSVDLHTH
CSYQLMLPEAIAIVCSPKHKDTGIFRLTNAGMLEVSACKKKGFHPHTKEP
RLFSICKHVLVKDIKIIVLDLR
Ligand information
Ligand ID
ZN
InChI
InChI=1S/Zn/q+2
InChIKey
PTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
Formula
Zn
Name
ZINC ION
ChEMBL
CHEMBL1236970
DrugBank
DB14532
ZINC
PDB chain
2znv Chain D Residue 2 [
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Receptor-Ligand Complex Structure
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PDB
2znv
Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains
Resolution
1.6 Å
Binding residue
(original residue number in PDB)
H362 C402 H408 H410
Binding residue
(residue number reindexed from 1)
H98 C138 H144 H146
Annotation score
4
Enzymatic activity
Enzyme Commision number
3.4.19.-
Gene Ontology
Molecular Function
GO:0008233
peptidase activity
GO:0008237
metallopeptidase activity
GO:0061578
K63-linked deubiquitinase activity
GO:0140492
metal-dependent deubiquitinase activity
Biological Process
GO:0016579
protein deubiquitination
GO:0070536
protein K63-linked deubiquitination
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Molecular Function
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Biological Process
External links
PDB
RCSB:2znv
,
PDBe:2znv
,
PDBj:2znv
PDBsum
2znv
PubMed
18758443
UniProt
Q96FJ0
|STALP_HUMAN AMSH-like protease (Gene Name=STAMBPL1)
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