Structure of PDB 2wyr Chain D Binding Site BS01

Receptor Information
>2wyr Chain D (length=325) Species: 70601 (Pyrococcus horikoshii OT3) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSMIEKLKKFTQIPGISGYEERIREEIIREIKDFADYKVDAIGNLIVELG
EGEERILFMAHMDEIGLLITGITDEGKLRFRKVGGIDDRLLYGRHVNVVT
EKGILDGVIGATPPHLSVIPWYDLVIDIGAESKEEALELVKPLDFAVFKK
HFSVLNGKYVSTRGLDDRFGVVALIEAIKDLVDHELEGKVIFAFTVQEEV
GLKGAKFLANHYYPQYAFAIDSFACCSPLTGDVKLGKGPVIRAVDNSAIY
SRDLARKVWSIAEKNGIEIQIGVTGGGTDASAFQDRSKTLALSVPIKYLH
SEVETLHLNDLEKLVKLIEALAFEL
Ligand information
Ligand IDCO
InChIInChI=1S/Co/q+2
InChIKeyXLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Co+2]
CACTVS 3.341[Co++]
FormulaCo
NameCOBALT (II) ION
ChEMBL
DrugBankDB14205
ZINC
PDB chain2wyr Chain D Residue 2325 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2wyr An Archaeal Peptidase Assembles Into Two Different Quaternary Structures: A Tetrahedron and a Giant Octahedron.
Resolution2.245 Å
Binding residue
(original residue number in PDB)		D1165 E1198 H1299
Binding residue
(residue number reindexed from 1)		D166 E199 H300
Annotation score3
Enzymatic activity
Enzyme Commision number 3.4.11.-
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2wyr, PDBe:2wyr, PDBj:2wyr
PDBsum2wyr
PubMed
UniProtO58255

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