Structure of PDB 2wy2 Chain D Binding Site BS01

Receptor Information

>2wy2 Chain D (length=103) Species: 562 (Escherichia coli)

KKHIYLFCSAGMSTSLLVSKMRAQAEKYEVPVIIEAFPETLAGEKGQNAD
VVLLGPQIAYMLPEIQRLLPNKPVEVIDSLLYGKVDGLGVLKAAVAAIKK
AAA

Ligand information

• Ligand ID: PO3
• InChI: InChI=1S/O3P/c1-4(2)3/q-3
• InChIKey: AQSJGOWTSHOLKH-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [O-][P-]([O-])=O
  ACDLabs 10.04: [O-][PH2-]([O-])=O
  OpenEye OEToolkits 1.5.0: [O-][P-](=O)[O-]
• Formula: O3 P
• Name: PHOSPHITE ION
• PDB chain: 2wy2 Chain D Residue 200

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2wy2 Solution Structure of the Iiachitobose-Iibchitobiose Complex of the N,N'-Diacetylchitobiose Branch of the Escherichia Coli Phosphotransfer System
• Resolution: N/A
• Binding residue (original residue number in PDB): C10 S11 A12 G13 M14 S15
• Binding residue (residue number reindexed from 1): C8 S9 A10 G11 M12 S13
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 2.7.1.196: protein-N(pi)-phosphohistidine--N,N'-diacetylchitobiose phosphotransferase.

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0008982 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
• GO:0016301 kinase activity
• GO:0090566 protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity

Biological Process

• GO:0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system
• GO:0016310 phosphorylation
• GO:1902815 N,N'-diacetylchitobiose import

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:1902495 transmembrane transporter complex

External links

• PDB: RCSB:2wy2, PDBe:2wy2, PDBj:2wy2
• PDBsum: 2wy2
• PubMed: 19959833
• UniProt: P69795|PTQB_ECOLI PTS system N,N'-diacetylchitobiose-specific EIIB component (Gene Name=chbB)