Structure of PDB 2va1 Chain D Binding Site BS01

Receptor Information
>2va1 Chain D (length=228) Species: 134821 (Ureaplasma parvum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRKQRIVIKISGACLKQNDSSIIDFIKINDLAEQIEKISKKYIVSIVLGG
GNIWRGSIAKELDMDRNLADNMGMMATIINGLALENALNHLNVNTIVLSA
IKCDKLVHESSANNIKKAIEKEQVMIFVAGTGFPYFTTDSCAAIRAAETE
SSIILMGKNGVDGVYDSAQFYEHITFNMALTQNLKVMDATALALCQENNI
NLLVFNIDKPNAIVDVLEKKNKYTIVSK
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain2va1 Chain D Residue 1236 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2va1 Structural and Functional Investigations of Ureaplasma Parvum Ump Kinase - a Potential Antibacterial Drug Target
Resolution2.5 Å
Binding residue
(original residue number in PDB)		S11 G12 G49 T138
Binding residue
(residue number reindexed from 1)		S11 G12 G49 T138
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.4.22: UMP kinase.
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0009041 UMP/dUMP kinase activity
GO:0016301 kinase activity
GO:0033862 UMP kinase activity
Biological Process
GO:0006221 pyrimidine nucleotide biosynthetic process
GO:0006225 UDP biosynthetic process
GO:0016310 phosphorylation
GO:0044210 'de novo' CTP biosynthetic process
GO:0046940 nucleoside monophosphate phosphorylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2va1, PDBe:2va1, PDBj:2va1
PDBsum2va1
PubMed18021254
UniProtQ9PPX6|PYRH_UREPA Uridylate kinase (Gene Name=pyrH)

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