Structure of PDB 2v3c Chain D Binding Site BS01

Receptor Information
>2v3c Chain D (length=401) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDKLGENLNKALNKLKAAAFVDKKLIKEVIKDIQRALIQADVNVKLVLKM
SKEIERRALEEKTPKGLSKKEHIIKIVYEELVKLLGEEAKKLELNPKKQN
VILLVGIQGSGKTTTAAKLARYIQKRGLKPALIAADTYRPAAYEQLKQLA
EKIHVPIYGDETRTKSPVDIVKEGMEKFKKADVLIIDTAGRHKEEKGLLE
EMKQIKEITNPDEIILVIDGTIGQQAGIQAKAFKEAVGEIGSIIVTKLDG
SAKGGGALSAVAETKAPIKFIGIGEGIDDLEPFDPKKFISRLLGMGDLES
LLEKAEDMVDEKTEESIDAIMRGKFTLNELMTQLEAIELTEAKIKKYKVI
ISSMTKEERENPKIIKASRIRRIARGSGTTENDVREVLRYYETTKNAIDK
L
Ligand information
>2v3c Chain M (length=96) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggcggugggggagcaucuccuguaggggagauguaacccccuuuaccugc
cgaaccccgccaggcccggaagggagcaacgguaggcaggacgucg
.<<<..<<<<<.<<<<<<<<<....>>>>>>>>>..>>>>>....<<<<<
<.....<<<...<.<<<....>>>..>..>>>..>>>>>>.>>>..
Receptor-Ligand Complex Structure
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PDB2v3c Interaction of Signal-Recognition Particle 54 Gtpase Domain and Signal-Recognition Particle RNA in the Free Signal-Recognition Particle.
Resolution2.5 Å
Binding residue
(original residue number in PDB)
K426 L427
Binding residue
(residue number reindexed from 1)
K400 L401
Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0008312 7S RNA binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0060090 molecular adaptor activity
Biological Process
GO:0006612 protein targeting to membrane
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0005737 cytoplasm
GO:0048500 signal recognition particle

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:2v3c, PDBe:2v3c, PDBj:2v3c
PDBsum2v3c
PubMed17846429
UniProtQ57565|SRP54_METJA Signal recognition particle 54 kDa protein (Gene Name=srp54)

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