Structure of PDB 2q6w Chain D Binding Site BS01
Receptor Information
>2q6w Chain D (length=180) Species:
9606
(Homo sapiens) [
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EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFA
SFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP
NVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLP
FLPSTEDVYDCRVEHWGLDEPLLKHWEFDA
Ligand information
>2q6w Chain F (length=12) Species:
9606
(Homo sapiens) [
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AWRSDEALPLGS
Receptor-Ligand Complex Structure
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PDB
2q6w
Crystallographic Structure of the Human Leukocyte Antigen DRA, DRB3*0101: Models of a Directional Alloimmune Response and Autoimmunity
Resolution
2.25 Å
Binding residue
(original residue number in PDB)
Q9 F24 I31 F32 S53 F54 N62 V65 N69 I72 M73
Binding residue
(residue number reindexed from 1)
Q7 F22 I29 F30 S51 F52 N60 V63 N67 I70 M71
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006955
immune response
GO:0019882
antigen processing and presentation
Cellular Component
GO:0016020
membrane
GO:0042613
MHC class II protein complex
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Biological Process
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Cellular Component
External links
PDB
RCSB:2q6w
,
PDBe:2q6w
,
PDBj:2q6w
PDBsum
2q6w
PubMed
17583734
UniProt
P01903
|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)
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