Structure of PDB 2p7p Chain D Binding Site BS01

Receptor Information
>2p7p Chain D (length=125) Species: 169963 (Listeria monocytogenes EGD-e) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MISGLSHITLIVKDLNKTTAFLQNIFNAEEIYSSSKEKFFLIAGLWICIM
EGDSLQERTYNHIAFQIQSEEVDEYTERIKALGVEMKPERPRVQGEGRSI
YFYDFDNHLFELHAGTLEERLKRYH
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain2p7p Chain D Residue 3001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2p7p Structure and Mechanism of the Genomically Encoded Fosfomycin Resistance Protein, FosX, from Listeria monocytogenes.
Resolution2.17 Å
Binding residue
(original residue number in PDB)		H69 Y108 E118
Binding residue
(residue number reindexed from 1)		H62 Y101 E111
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0046677 response to antibiotic
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2p7p, PDBe:2p7p, PDBj:2p7p
PDBsum2p7p
PubMed17567049
UniProtQ8Y6I2|FOSX_LISMO Fosfomycin resistance protein FosX (Gene Name=fosX)

[Back to BioLiP]