Structure of PDB 2nz0 Chain D Binding Site BS01

Receptor Information
>2nz0 Chain D (length=136) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWR
TTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHY
PRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2nz0 Chain D Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2nz0 Structural basis for modulation of Kv4 K(+) channels by auxiliary KChIP subunits.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		H104 C131 C132
Binding residue
(residue number reindexed from 1)		H99 C126 C127
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005249 voltage-gated potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0051260 protein homooligomerization
Cellular Component
GO:0008076 voltage-gated potassium channel complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2nz0, PDBe:2nz0, PDBj:2nz0
PDBsum2nz0
PubMed17187064
UniProtQ9UK17|KCND3_HUMAN A-type voltage-gated potassium channel KCND3 (Gene Name=KCND3)

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