Structure of PDB 2ixp Chain D Binding Site BS01

Receptor Information
>2ixp Chain D (length=310) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLDRVDWPHATFSTPVKRIFDTQTTLDFQSSLAIHRIKYHLHKYTTLISH
CSDPDPHATASSIAMVNGLMGVLDKLAHLIDETPPLGNLACREWHHKLDE
RLPQWLQEMLPSEYHEVVPELQYYLGNSFGSSTRLDYGTGHELSFMATVA
ALDMLGMFPHMRGADVFLLFNKYYTIMRRLILTYTLEPAGSHGVWGLDDH
FHLVYILGSSQWQLLDAQAPLQPREILDKSLVREYKDTNFYCQGINFINE
VKMGPFEEHSPILYDIAVTVPRWSKVCKGLLKMYSVEVLKKFPVVQHFWF
GTGFFPWVNI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2ixp Crystal structure of the PP2A phosphatase activator: implications for its PP2A-specific PPIase activity.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
W202 I269 D272 I273 G286
Binding residue
(residue number reindexed from 1)
W195 I262 D265 I266 G279
Enzymatic activity
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Gene Ontology
Molecular Function
GO:0019211 phosphatase activator activity

View graph for
Molecular Function
External links
PDB RCSB:2ixp, PDBe:2ixp, PDBj:2ixp
PDBsum2ixp
PubMed16885030
UniProtP40454|PTPA1_YEAST Serine/threonine-protein phosphatase 2A activator 1 (Gene Name=RRD1)

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