Structure of PDB 2ixp Chain D Binding Site BS01
Receptor Information
>2ixp Chain D (length=310) Species:
4932
(Saccharomyces cerevisiae) [
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SLDRVDWPHATFSTPVKRIFDTQTTLDFQSSLAIHRIKYHLHKYTTLISH
CSDPDPHATASSIAMVNGLMGVLDKLAHLIDETPPLGNLACREWHHKLDE
RLPQWLQEMLPSEYHEVVPELQYYLGNSFGSSTRLDYGTGHELSFMATVA
ALDMLGMFPHMRGADVFLLFNKYYTIMRRLILTYTLEPAGSHGVWGLDDH
FHLVYILGSSQWQLLDAQAPLQPREILDKSLVREYKDTNFYCQGINFINE
VKMGPFEEHSPILYDIAVTVPRWSKVCKGLLKMYSVEVLKKFPVVQHFWF
GTGFFPWVNI
Ligand information
>2ixp Chain H (length=6) Species:
32630
(synthetic construct) [
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cAAPKc
Receptor-Ligand Complex Structure
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PDB
2ixp
Crystal structure of the PP2A phosphatase activator: implications for its PP2A-specific PPIase activity.
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
W202 I269 D272 I273 G286
Binding residue
(residue number reindexed from 1)
W195 I262 D265 I266 G279
Enzymatic activity
Enzyme Commision number
5.2.1.8
: peptidylprolyl isomerase.
Gene Ontology
Molecular Function
GO:0019211
phosphatase activator activity
View graph for
Molecular Function
External links
PDB
RCSB:2ixp
,
PDBe:2ixp
,
PDBj:2ixp
PDBsum
2ixp
PubMed
16885030
UniProt
P40454
|PTPA1_YEAST Serine/threonine-protein phosphatase 2A activator 1 (Gene Name=RRD1)
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