Structure of PDB 2iic Chain D Binding Site BS01

Receptor Information
>2iic Chain D (length=302) Species: 5741 (Giardia intestinalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DAIPEVKAILEAKNEEELVTFTSRWSAEERKELRTQFQDTTGLEFIAFLK
KCIKNGPYEDVMALGWDCNISARVNVIKKAMKNVNDFRAIHDVVLIATPD
ERLKLAQAYKEKTGNDLLQDFVDQIPLTSAASYLCHLAIRENRTPRGSVA
SDAEVLKHNLIDADEPDHEAVVRLIITSTADEYKEINHRFEVLTGKSVQE
AIETRYADKENARGLCIAHYYNLAPARAVAYAFHSAVETQNDDMAYEQAA
RITGLFHDLHKFAWVHYACWGVMRDDILSRFQSKEANKVNFRDACLMFWK
LA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2iic Chain D Residue 404 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2iic Apo and Calcium-bound Crystal Structures of Alpha-11 Giardin, an Unusual Annexin from Giardia lamblia
Resolution2.93 Å
Binding residue
(original residue number in PDB)		K53 K57 N58 E62
Binding residue
(residue number reindexed from 1)		K50 K54 N55 E59
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005544 calcium-dependent phospholipid binding
GO:0046872 metal ion binding
Biological Process
GO:0007010 cytoskeleton organization
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2iic, PDBe:2iic, PDBj:2iic
PDBsum2iic
PubMed17355882
UniProtQ4VPP2

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