Structure of PDB 2hvy Chain D Binding Site BS01

Receptor Information
>2hvy Chain D (length=121) Species: 2261 (Pyrococcus furiosus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPSYVKFEVPKELAEKALQAVEIARDTGKIRKGTNETTKAVERGQAKLVI
IAEDVDPEEIVAHLPPLCEEKEIPYIYVPSKKELGAAAGIEVAAASVAII
EPGKARDLVEEIAMKVKELMK
Ligand information
>2hvy Chain E (length=61) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggguccgccuugagugcccgggugagaagcaugaucccggguaauuaugg
cggacccacag
<<<<<<<<<......<<<<<<<.............>>>>>>>......>>
>>>>>>>....
Receptor-Ligand Complex Structure
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PDB2hvy Crystal structure of an H/ACA box ribonucleoprotein particle
Resolution2.3 Å
Binding residue
(original residue number in PDB)		R34 K35 G36 T37 N38 E39 K42 R46 D59 I63 K84 I93 V95 A96 A97 A98
Binding residue
(residue number reindexed from 1)		R31 K32 G33 T34 N35 E36 K39 R43 D56 I60 K81 I90 V92 A93 A94 A95
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0004526 ribonuclease P activity
GO:0019843 rRNA binding
Biological Process
GO:0001682 tRNA 5'-leader removal
GO:0006364 rRNA processing
GO:0006412 translation
GO:0008033 tRNA processing
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:2hvy, PDBe:2hvy, PDBj:2hvy
PDBsum2hvy
PubMed16943774
UniProtQ8U160|RL7A_PYRFU Large ribosomal subunit protein eL8 (Gene Name=rpl7ae)

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