Structure of PDB 2hqh Chain D Binding Site BS01

Receptor Information
>2hqh Chain D (length=72) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLRVGSRVEVIGKGHRGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQG
RKYFTCDEGHGIFVRQSQIQVF
Ligand information
>2hqh Chain H (length=22) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PYCEICEMFGHWATNCNDDETF
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2hqh CLIP170 autoinhibition mimics intermolecular interactions with p150Glued or EB1.
Resolution1.8 Å
Binding residue
(original residue number in PDB)
F52 T54 G55 K56 W57 K68 N69 I87 F88 R90 Q91 S92 Q93
Binding residue
(residue number reindexed from 1)
F27 T29 G30 K31 W32 K43 N44 I62 F63 R65 Q66 S67 Q68
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2hqh, PDBe:2hqh, PDBj:2hqh
PDBsum2hqh
PubMed17828275
UniProtQ14203|DCTN1_HUMAN Dynactin subunit 1 (Gene Name=DCTN1)

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