Structure of PDB 2f53 Chain D Binding Site BS01
Receptor Information
>2f53 Chain D (length=193) Species:
9606
(Homo sapiens) [
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MKQEVTQIPAALSVPEGENLVLNCSFTDSAIYNLQWFRQDPGKGLTSLLL
IPFWQREQTSGRLNASLDKSSGRSTLYIAASQPGDSATYLCAVRPTSGGS
YIPTFGRGTSLIVHPYIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVS
QSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFN
Ligand information
>2f53 Chain C (length=9) Species:
9606
(Homo sapiens) [
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SLLMWITQC
Receptor-Ligand Complex Structure
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PDB
2f53
Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
Y30 P93 T94 S95 G97 Y99
Binding residue
(residue number reindexed from 1)
Y32 P95 T96 S97 G99 Y101
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2f53
,
PDBe:2f53
,
PDBj:2f53
PDBsum
2f53
PubMed
16600963
UniProt
P01848
|TRAC_HUMAN T cell receptor alpha chain constant (Gene Name=TRAC)
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