Structure of PDB 2eul Chain D Binding Site BS01

Receptor Information
>2eul Chain D (length=156) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAREVKLTKAGYERLMQQLERERERLQEATKILQELMESSDDYDDSGLEA
AKQEKARIEARIDSLEDILSRAVILEEGSGEVIGLGSVVELEDPLSGERL
SVQVVSPAEANVLDTPMKISDASPMGKALLGHRVGDVLSLDTPKGRREFR
VVAIHG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2eul Chain D Residue 418 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2eul Regulation through the RNA Polymerase Secondary Channel: STRUCTURAL AND FUNCTIONAL VARIABILITY OF THE COILED-COIL TRANSCRIPTION FACTORS.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		E54 R57
Binding residue
(residue number reindexed from 1)		E54 R57
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0046872 metal ion binding
GO:0070063 RNA polymerase binding
Biological Process
GO:0006354 DNA-templated transcription elongation
GO:0032784 regulation of DNA-templated transcription elongation

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Molecular Function
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Biological Process
External links
PDB RCSB:2eul, PDBe:2eul, PDBj:2eul
PDBsum2eul
PubMed16298991
UniProtQ5SJG6|GFH1_THET8 Transcription inhibitor protein Gfh1 (Gene Name=gfh1)

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