Structure of PDB 2e6c Chain D Binding Site BS01

Receptor Information

>2e6c Chain D (length=234) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MRILVTNDDGIYSPGLWALAEAASQFGEVFVAAPDTHAITIAHPVRAYPH
PSPLHAPHFPAYRVRGTPADCVALGLHLFGPVDLVLSGVNLGSNLGHEIW
HSGTVAAAKQGYLFGLSAAAFSVPLNGEVPDFAGLRPWLLRTLETLLRLE
RPFLVNVNLPLRPKGFLWTRQSVRAYEGVVIPGEDPMGRPFYWFAPRPLK
EAEEGTDRWAVAQGFVSATPLRLDLTDETRLQPT

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

2e6c Chain D Residue 3301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2e6c Crystal Structure of the Stationary Phase Survival Protein SurE with Metal Ion and AMP
Resolution	2.05 Å
Binding residue (original residue number in PDB)	D8 D9 N96
Binding residue (residue number reindexed from 1)	D8 D9 N90
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.1.3.5: 5'-nucleotidase.

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0004309	exopolyphosphatase activity
GO:0008252	nucleotidase activity
GO:0008253	5'-nucleotidase activity
GO:0008254	3'-nucleotidase activity
GO:0016787	hydrolase activity
GO:0046872	metal ion binding
GO:0106411	XMP 5'-nucleosidase activity

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Cellular Component

External links

PDB	RCSB:2e6c, PDBe:2e6c, PDBj:2e6c
PDBsum	2e6c
PubMed	17561111
UniProt	Q53W92\|SURE_THET8 5'-nucleotidase SurE (Gene Name=surE)

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