Structure of PDB 2e52 Chain D Binding Site BS01

Receptor Information
>2e52 Chain D (length=298) Species: 71421 (Haemophilus influenzae Rd KW20) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSALEKLLSLIENLTNQEFKQATNSLISFIYKLNRNEVIELVRSIGILPE
AIKPSSTQEKLFSKAGDIVLAKAFQLLNLNSKPLEQRGNAGDVIALSKEF
NYGLVADAKSFRLSRTAKNQKDFKVKALSEWREDKDYAVLTAPFFQYPTT
KSQIFKQSLDENVLLFSWEHLAILLQLDLEETNIFSFEQLWNFPKKQSKK
TSVSDAENNFMRDFNKYFMDLFKIDKDTLNQLLQKEINFIEERSLIEKEY
WKKQINIIKNFTREEAIEALLKDINMSSKIETIDSFIKGIKSNDRLYL
Ligand information
Receptor-Ligand Complex Structure
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PDB2e52 Structures of restriction endonuclease HindIII in complex with its cognate DNA and divalent cations
Resolution2.0 Å
Binding residue
(original residue number in PDB)		F20 K21 S56 T58 K61 E86 R88 A118 N120 Q121 K122 P149 T150 T151 K152 S153 Q154 N276
Binding residue
(residue number reindexed from 1)		F19 K20 S55 T57 K60 E85 R87 A117 N119 Q120 K121 P148 T149 T150 K151 S152 Q153 N275
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:2e52, PDBe:2e52, PDBj:2e52
PDBsum2e52
PubMed19966419
UniProtP43870|T2D3_HAEIN Type II restriction enzyme HindIII (Gene Name=hindIIIR)

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