Structure of PDB 2e3k Chain D Binding Site BS01
Receptor Information
>2e3k Chain D (length=109) Species:
9606
(Homo sapiens) [
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MEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDL
STVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVF
EFRYAKMPD
Ligand information
>2e3k Chain R (length=13) Species:
559292
(Saccharomyces cerevisiae S288C) [
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RGKGGKGLGKGGA
Receptor-Ligand Complex Structure
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PDB
2e3k
Structural basis for diacetylated histone H4 tail recognition by the second bromodomain of human BRD2
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
V376 L383 N429 P430 H433 V435
Binding residue
(residue number reindexed from 1)
V30 L37 N83 P84 H87 V89
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2e3k
,
PDBe:2e3k
,
PDBj:2e3k
PDBsum
2e3k
PubMed
UniProt
P25440
|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)
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