Structure of PDB 2e3k Chain D Binding Site BS01

Receptor Information
>2e3k Chain D (length=109) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDL
STVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVF
EFRYAKMPD
Ligand information
>2e3k Chain R (length=13) Species: 559292 (Saccharomyces cerevisiae S288C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RGKGGKGLGKGGA
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2e3k Structural basis for diacetylated histone H4 tail recognition by the second bromodomain of human BRD2
Resolution2.3 Å
Binding residue
(original residue number in PDB)
V376 L383 N429 P430 H433 V435
Binding residue
(residue number reindexed from 1)
V30 L37 N83 P84 H87 V89
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2e3k, PDBe:2e3k, PDBj:2e3k
PDBsum2e3k
PubMed
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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