Structure of PDB 2bkb Chain D Binding Site BS01

Receptor Information

>2bkb Chain D (length=192) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGK
SLEEIIRSSEGGVFNNAAEVWNHTFYWNCLAPNAGGEPTGKVAEAIAASF
GSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDAT
PLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA

Ligand information

InChI=1S/Fe/q+2

CWYNVVGOOAEACU-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Fe+2]
CACTVS 3.341	[Fe++]

Formula

Name

FE (II) ION

PDB chain

2bkb Chain D Residue 1393 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	2bkb The Crucial Importance of Chemistry in the Structure-Function Link: Manipulating Hydrogen Bonding in Iron-Containing Superoxide Dismutase.
Resolution	1.7 Å
Binding residue (original residue number in PDB)	H226 H273 D356 H360
Binding residue (residue number reindexed from 1)	H26 H73 D156 H160
Annotation score	1

Enzymatic activity

Enzyme Commision number

1.15.1.1: superoxide dismutase.

Gene Ontology

	Molecular Function
GO:0004784	superoxide dismutase activity
GO:0005506	iron ion binding
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding

	Biological Process
GO:0000303	response to superoxide
GO:0006801	superoxide metabolic process
GO:0019430	removal of superoxide radicals

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016020	membrane

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Cellular Component

External links

PDB	RCSB:2bkb, PDBe:2bkb, PDBj:2bkb
PDBsum	2bkb
PubMed	16430211
UniProt	P0AGD3\|SODF_ECOLI Superoxide dismutase [Fe] (Gene Name=sodB)

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