Structure of PDB 2av1 Chain D Binding Site BS01

Receptor Information
>2av1 Chain D (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGQTRAVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>2av1 Chain F (length=9) Species: 11927 (Human T-cell lymphotrophic virus type 1 (Caribbean isolate)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LLFGYPVYV
Receptor-Ligand Complex Structure
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PDB2av1 Unraveling a Hotspot for TCR Recognition on HLA-A2: Evidence Against the Existence of Peptide-independent TCR Binding Determinants.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		Y7 Q63 T73 V76 D77 Y84 R97 Y99 T143 K146 W147 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)		Y7 Q63 T73 V76 D77 Y84 R97 Y99 T143 K146 W147 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2av1, PDBe:2av1, PDBj:2av1
PDBsum2av1
PubMed16197958
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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