Structure of PDB 2akc Chain D Binding Site BS01

Receptor Information
>2akc Chain D (length=219) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MQPFHSPEESVNSQFYLPPPPGNDDPAFRYDKEAYFKGYAIKGSPRWKQA
AEDADISVENIARIFSPVVGAKISPKDTPETWNMLQNLLKVGGYYATASA
KKYYMRTRPFVLFNHSTCRPEDENTLRKDGSYPSGHTAYSTLLALVLSQA
RPERAQELARRGWEFGQSRVICGAHWQSDVDAGRYVGAVEFARLQTIPAF
QKSLAKVREELNDKNNLLS
Ligand information
Ligand IDWO4
InChIInChI=1S/4O.W/q;;2*-1;
InChIKeyPBYZMCDFOULPGH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-][W](=O)(=O)[O-]
ACDLabs 10.04
CACTVS 3.341		[O-][W]([O-])(=O)=O
FormulaO4 W
NameTUNGSTATE(VI)ION
ChEMBL
DrugBank
ZINC
PDB chain2akc Chain D Residue 504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2akc Structure and Mutational Analysis of the PhoN Protein of Salmonella typhimurium Provide Insight into Mechanistic Details.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		R130 S156 G157 H158 R191 H197
Binding residue
(residue number reindexed from 1)		R108 S134 G135 H136 R169 H175
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H158 R191 H197 D201
Catalytic site (residue number reindexed from 1) H136 R169 H175 D179
Enzyme Commision number 3.1.3.2: acid phosphatase.
Gene Ontology
Molecular Function
GO:0003993 acid phosphatase activity
GO:0016787 hydrolase activity
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:2akc, PDBe:2akc, PDBj:2akc
PDBsum2akc
PubMed17263560
UniProtQ8KRU6

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