Structure of PDB 1zei Chain D Binding Site BS01

Receptor Information
>1zei Chain D (length=53) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTDKAAKGIVEQCCTSICSLYQLEN
YCN
Ligand information
Ligand IDCRS
InChIInChI=1S/C7H8O/c1-6-3-2-4-7(8)5-6/h2-5,8H,1H3
InChIKeyRLSSMJSEOOYNOY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04Oc1cc(ccc1)C
OpenEye OEToolkits 1.5.0Cc1cccc(c1)O
CACTVS 3.341Cc1cccc(O)c1
FormulaC7 H8 O
NameM-CRESOL
ChEMBLCHEMBL298312
DrugBankDB01776
ZINCZINC000000897141
PDB chain1zei Chain D Residue 54 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1zei Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		L11 C38 I42 C43
Binding residue
(residue number reindexed from 1)		L11 C38 I42 C43
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:1zei, PDBe:1zei, PDBj:1zei
PDBsum1zei
PubMed9708987
UniProtP01315|INS_PIG Insulin (Gene Name=INS)

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