Structure of PDB 1x6m Chain D Binding Site BS01

Receptor Information

>1x6m Chain D (length=194) Species: 266 (Paracoccus denitrificans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MVDTSGVKIHPAVDNGIKPAQPGFAGGTLHCKCSTNPVRVAVRAQTAHNH
VCGCTKCWKPEGAIFSQVAVVGRDALEVLEGAEKLEIVNAEAPIQRHRCR
DCGVHMYGRIENRDHPFYGLDFVHTELSDEDGWSAPEFAAFVSSIIESGV
DPSRMEAIRARLRELGLEPYDALSPPLMDAIATHIAKRSGALAA

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

1x6m Chain D Residue 200 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1x6m A dynamic zinc redox switch
Resolution	2.35 Å
Binding residue (original residue number in PDB)	C33 C35 C101 C104
Binding residue (residue number reindexed from 1)	C31 C33 C99 C102
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	C54 C56 C59
Catalytic site (residue number reindexed from 1)	C52 C54 C57
Enzyme Commision number	4.4.1.22: S-(hydroxymethyl)glutathione synthase.

Gene Ontology

	Molecular Function
GO:0008270	zinc ion binding
GO:0016829	lyase activity
GO:0016846	carbon-sulfur lyase activity
GO:0046872	metal ion binding
GO:0051907	S-(hydroxymethyl)glutathione synthase activity

	Biological Process
GO:0046294	formaldehyde catabolic process

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Molecular Function

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Biological Process

External links

PDB	RCSB:1x6m, PDBe:1x6m, PDBj:1x6m
PDBsum	1x6m
PubMed	15548539
UniProt	Q51669\|GFA_PARDE Glutathione-dependent formaldehyde-activating enzyme (Gene Name=gfa)

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